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Symbol
Name
ID

Hdac4
histone deacetylase 4
MGI:3036234

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Ataxia

Dysdiadochokinesis

Progressive cerebellar ataxia

Slurred speech

Choreoathetosis

Myoclonus

Tremor

Intention tremor

Delayed speech and language development

Dysarthria

Reduced tendon reflexes

Dystonia

Inability to walk

Seizure

Disease(s) Associated with HDAC4

ataxia telangiectasia

Mouse Phenotypes		nervous system phenotype	environmentally induced seizures	convulsive seizures	tonic seizures	abnormal spike wave discharge	exencephaly	abnormal motor nerve collateral sprouting
Availability	Mouse Genotype	nervous system phenotype	environmentally induced seizures	convulsive seizures	tonic seizures	abnormal spike wave discharge	exencephaly	abnormal motor nerve collateral sprouting
	Hdac4^{Gt(OST361114)Lex}/Hdac4^{Gt(OST361114)Lex}	*
	Hdac4^tm1Eno/Hdac4^tm1Eno
	Hdac4^tm2.1Eno/Hdac4^tm2.1Eno Tg(Myog-cre)1Eno/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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