Symbol
Name
ID

Arfgef2
ADP ribosylation factor guanine nucleotide exchange factor 2
MGI:2139354

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Cerebral hemorrhage

Microcephaly

Progressive microcephaly

Stroke

Abnormal nervous system morphology

Thin corpus callosum

Hypoplasia of the corpus callosum

Cerebellar hypoplasia

Abnormality of neuronal migration

Gray matter heterotopia

Periventricular heterotopia

Periventricular nodular heterotopia

Tetraparesis

Hypsarrhythmia

Reduced eye contact

Delayed speech and language development

Intellectual disability

Intellectual disability, mild

Intellectual disability, severe

Global developmental delay

Mild global developmental delay

Seizure

Focal-onset seizure

Focal motor seizure

Infantile spasms

Disease(s) Associated with ARFGEF2

periventricular nodular heterotopia

Mouse Phenotypes		nervous system phenotype	abnormal neuronal migration	abnormal cerebral cortex morphology	exencephaly	ectopic neuron
Availability	Mouse Genotype	nervous system phenotype	abnormal neuronal migration	abnormal cerebral cortex morphology	exencephaly	ectopic neuron
	Arfgef2^tm1Itl/Arfgef2^tm1Itl	*
	Arfgef2^tm1Itl/Arfgef2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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