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Symbol
Name
ID

Crb1
crumbs family member 1, photoreceptor morphogenesis associated
MGI:2136343

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Encephalocele	Photophobia	Aplasia/Hypoplasia of the cerebellar vermis	Abnormality of neuronal migration	Hemiplegia/hemiparesis	Eye poking	Intellectual disability	Hyperreflexia	Global developmental delay	Seizure
Disease(s) Associated with CRB1	Encephalocele	Photophobia	Aplasia/Hypoplasia of the cerebellar vermis	Abnormality of neuronal migration	Hemiplegia/hemiparesis	Eye poking	Intellectual disability	Hyperreflexia	Global developmental delay	Seizure
cone-rod dystrophy
Leber congenital amaurosis
Leber congenital amaurosis 8
retinitis pigmentosa

Mouse Phenotypes		abnormal Muller cell morphology	decreased retina photoreceptor cell number	abnormal retina photoreceptor morphology	abnormal photoreceptor inner segment morphology	short photoreceptor inner segment	short photoreceptor outer segment	photoreceptor outer segment degeneration	retina photoreceptor degeneration
Availability	Mouse Genotype	abnormal Muller cell morphology	decreased retina photoreceptor cell number	abnormal retina photoreceptor morphology	abnormal photoreceptor inner segment morphology	short photoreceptor inner segment	short photoreceptor outer segment	photoreceptor outer segment degeneration	retina photoreceptor degeneration
	Crb1^em3Jnk/Crb1^em3Jnk
	Crb1^em4Jnk/Crb1^em4Jnk
	Crb1^rd8/Crb1^rd8
	Crb1^tm1Wij/Crb1^tm1Wij

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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