About Help FAQ

Symbol
Name
ID

Hspb8
heat shock protein 8
MGI:2135756

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Areflexia of lower limbs	Hyporeflexia of lower limbs	Decreased number of large peripheral myelinated nerve fibers	Peripheral axonal neuropathy	Paralysis	Decreased amplitude of sensory action potentials	Areflexia	Hyporeflexia	Distal sensory impairment
Disease(s) Associated with HSPB8	Areflexia of lower limbs	Hyporeflexia of lower limbs		Peripheral axonal neuropathy	Paralysis	Decreased amplitude of sensory action potentials	Areflexia	Hyporeflexia	Distal sensory impairment
autosomal dominant distal hereditary motor neuronopathy 2
Charcot-Marie-Tooth disease axonal type 2L

Mouse Phenotypes		nervous system phenotype	amyloid beta deposits	abnormal sciatic nerve morphology	axon degeneration	abnormal action potential
Availability	Mouse Genotype	nervous system phenotype	amyloid beta deposits	abnormal sciatic nerve morphology	axon degeneration	abnormal action potential
	Hspb8^tm1.1Vti/Hspb8^tm1.1Vti	*
	Hspb8^tm1Vti/Hspb8^tm1Vti
	Hspb8^tm1Vti/Hspb8⁺
	Tg(Myh6/tetO-Hspb8K141N)#Atsa/0 Tg(Myh6-tTA)55Rbns/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23