Symbol Name ID |
Atl1
atlastin GTPase 1 MGI:1921241 |
Darker colors indicate more annotations |
Human Phenotypes | Ankle clonus |
Lower limb spasticity |
Spastic paraplegia |
Spastic gait |
Frequent falls |
Peripheral axonal neuropathy |
Hypoplasia of the corpus callosum |
Degeneration of the lateral corticospinal tracts |
Bradykinesia |
Babinski sign |
Paraplegia |
Dysarthria |
Intellectual disability, mild |
Hyperreflexia |
Lower limb hyperreflexia |
Gait disturbance |
Tip-toe gait |
Motor delay |
Peripheral neuropathy |
Distal sensory impairment of all modalities |
Hyperesthesia |
Paresthesia |
Distal sensory impairment |
Impaired vibratory sensation |
Impaired vibration sensation in the lower limbs |
Disease(s) Associated with ATL1 | |||||||||||||||||||||||||
hereditary sensory neuropathy type 1D | |||||||||||||||||||||||||
hereditary spastic paraplegia 3A |
Mouse Phenotypes | abnormal corticospinal tract morphology |
abnormal myelin sheath morphology |
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Availability | Mouse Genotype | ||
Atl1tm1.1Cbla/Atl1tm1.1Cbla | |||
Atl1tm1.2Cbla/Atl1tm1.2Cbla |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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