|
Symbol Name ID |
Tubb2b
tubulin, beta 2B class IIB MGI:1920960 |
| Darker colors indicate more annotations |
| Human Phenotypes | Microcephaly |
Drooling |
Abnormal brainstem morphology |
Hypoplasia of the pons |
Hypoplasia of the brainstem |
Lateral ventricle dilatation |
Lissencephaly |
Pachygyria |
Polymicrogyria |
Perisylvian polymicrogyria |
Unilateral polymicrogyria |
Cortical dysplasia |
Frontoparietal cortical dysplasia |
Abnormal caudate nucleus morphology |
Dysgenesis of the basal ganglia |
Abnormal corpus callosum morphology |
Agenesis of corpus callosum |
Partial agenesis of the corpus callosum |
Hypoplasia of the corpus callosum |
Cavum septum pellucidum |
Schizencephaly |
Cerebellar vermis hypoplasia |
Cerebellar hypoplasia |
Cerebellar atrophy |
Gray matter heterotopia |
Oromotor apraxia |
Hemiparesis |
Tetraparesis |
Abnormal temper tantrums |
Attention deficit hyperactivity disorder |
Cognitive impairment |
Intellectual disability |
Global developmental delay |
Motor delay |
Specific learning disability |
Seizure |
Focal-onset seizure |
Generalized-onset seizure |
Infantile spasms |
| Disease(s) Associated with TUBB2B | |||||||||||||||||||||||||||||||||||||||
| complex cortical dysplasia with other brain malformations 7 |
| Mouse Phenotypes | increased neuron apoptosis |
abnormal neuronal precursor proliferation |
abnormal cortical plate morphology |
hydrocephaly |
abnormal brain interneuron morphology |
decreased midbrain size |
enlarged brain ventricles |
abnormal choroid plexus morphology |
absent corpus callosum |
absent anterior commissure |
abnormal brain internal capsule morphology |
abnormal basal ganglion morphology |
abnormal telencephalon morphology |
abnormal cerebral cortex morphology |
abnormal primary motor cortex morphology |
abnormal somatosensory cortex morphology |
thin cerebral cortex |
small olfactory bulb |
small cerebellum |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Tubb2bbrdp/Tubb2bbrdp | ||||||||||||||||||||
| Tubb2bem1Rstot/Tubb2bem1Rstot | ||||||||||||||||||||
| Tubb2bbrdp/Tubb2b+ | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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