Symbol
Name
ID

Ush1c
USH1 protein network component harmonin
MGI:1919338

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Cerebral cortical atrophy

Subcortical cerebral atrophy

Aplasia/Hypoplasia of the cerebellum

Ataxia

Depression

Anxiety

Psychosis

Schizophrenia

Hallucinations

Hyperacusis

Cognitive impairment

Intellectual disability

Global developmental delay

Motor delay

Disease(s) Associated with USH1C

Usher syndrome

Usher syndrome type 1

Mouse Phenotypes

abnormal cochlear hair cell morphology

abnormal cochlear hair cell stereociliary bundle morphology

abnormal cochlear hair cell inter-stereocilial links morphology

abnormal cochlear hair bundle tip links morphology

abnormal inner hair cell stereociliary bundle morphology

abnormal orientation of inner hair cell stereociliary bundles

abnormal orientation of cochlear hair cell stereociliary bundles

abnormal orientation of outer hair cell stereociliary bundles

abnormal outer hair cell stereociliary bundle morphology

cochlear inner hair cell degeneration

abnormal cochlear outer hair cell morphology

cochlear outer hair cell degeneration

vestibular hair cell degeneration

abnormal hair cell mechanoelectric transduction

cochlear ganglion degeneration

Availability

Mouse Genotype

Ush1c^dfcr-2J/Ush1c^dfcr-2J

Ush1c^dfcr/Ush1c^dfcr

Ush1c^tm1.1Mull/Ush1c^tm1.1Mull

Ush1c^tm1.1Ugds/Ush1c^tm1.1Ugds

Ush1c^tm1Xzl/Ush1c^tm1Xzl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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