|
Symbol Name ID |
Cic
capicua transcriptional repressor MGI:1918972 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebral palsy |
Chorea |
Myoclonus |
Delayed speech and language development |
Poor speech |
Anxiety |
Perseverative thought |
Autistic behavior |
Hyperactivity |
Attention deficit hyperactivity disorder |
Motor stereotypy |
Recurrent hand flapping |
Intellectual disability |
Sleep abnormality |
Developmental regression |
Global developmental delay |
Motor delay |
Bilateral tonic-clonic seizure |
Focal impaired awareness seizure |
Generalized non-motor (absence) seizure |
Myoclonic seizure |
| Disease(s) Associated with CIC | |||||||||||||||||||||
| autosomal dominant intellectual developmental disorder 45 |
| Mouse Phenotypes | nervous system phenotype |
decreased brain weight |
abnormal dentate gyrus morphology |
decreased dentate gyrus size |
abnormal cerebral cortex morphology |
decreased cerebral cortex cell number |
thin cerebral cortex |
abnormal cerebellar layer morphology |
abnormal pyramidal neuron dendrite morphology |
decreased neurotransmitter release |
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| Availability | Mouse Genotype | ||||||||||
| Cictm1.1Jip/Cictm1.1Jip Tg(Nes-cre)1Kln/0 (conditional) |
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| Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi Emx1tm1(cre)Krj/Emx1+ (conditional) |
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| Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi Neurod6tm1(cre)Kan/Neurod6+ (conditional) |
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| Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi Tg(Otp-cre)1Hzo/0 (conditional) |
* | ||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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