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Symbol
Name
ID
Hdac8
histone deacetylase 8
MGI:1917565
Phenotype annotations related to nervous system
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Ventriculomegaly
Absent speech
Delayed speech and language development
Poor speech
Stuttering
Emotional lability
Atypical behavior
Happy demeanor
Intellectual disability
Global developmental delay
Specific learning disability
Seizure
Disease(s) Associated with HDAC8
Cornelia de Lange syndrome 5
Wilson-Turner syndrome

Mouse Phenotypes
intracranial hemorrhage
exencephaly
Availability Mouse Genotype
Hdac8tm1.2Eno/Hdac8tm1.2Eno !
Hdac8tm1.2Eno/Hdac8+ !
Hdac8tm1.2Eno/Y !
Hdac8tm1.1Eno/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory