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Symbol
Name
ID

Pink1
PTEN induced putative kinase 1
MGI:1916193

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Bradykinesia	Parkinsonism	Resting tremor	Depression	Anxiety	Dementia	Hyperreflexia	Dystonia	Postural instability
Disease(s) Associated with PINK1
Parkinson's disease 6

Mouse Phenotypes

nervous system phenotype

increased neuron apoptosis

abnormal cerebral cortex morphology

abnormal olfactory bulb glomerular layer morphology

abnormal innervation

abnormal dopaminergic neuron morphology

abnormal nervous system physiology

abnormal nervous system electrophysiology

abnormal neuron physiology

reduced long-term potentiation

reduced long-term depression

Availability

Mouse Genotype

Pink1^tm1.1Wrst/Pink1^tm1.1Wrst

*

Pink1^tm1Aub/Pink1^tm1Aub

*

Pink1^tm1Hlw/Pink1^tm1Hlw

Pink1^tm1Lex/Pink1^tm1Lex

Pink1^tm1Shn/Pink1^tm1Shn

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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