Symbol
Name
ID

Mast1
microtubule associated serine/threonine kinase 1
MGI:1861901

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Oculomotor apraxia

Hypoplasia of the brainstem

Ventriculomegaly

Simplified gyral pattern

Thick corpus callosum

Cerebellar vermis hypoplasia

Cerebellar hypoplasia

Periventricular heterotopia

Truncal ataxia

Absent speech

Intellectual disability

Inability to walk

Unsteady gait

Global developmental delay

Seizure

Disease(s) Associated with MAST1

mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations

Mouse Phenotypes		nervous system phenotype	increased neuron apoptosis	increased corpus callosum size	thin cerebral cortex	thin cerebellar granule layer	thin cerebellar molecular layer	cerebellum hypoplasia	abnormal innervation
Availability	Mouse Genotype	nervous system phenotype	increased neuron apoptosis	increased corpus callosum size	thin cerebral cortex	thin cerebellar granule layer	thin cerebellar molecular layer	cerebellum hypoplasia	abnormal innervation
	Mast1^em1Dak/Mast1^em1Dak
	Mast1^em2Dak/Mast1^em2Dak	*
	Mast1^em1Dak/Mast1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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