About Help FAQ

Symbol
Name
ID

Nbn
nibrin
MGI:1351625

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Glioma	Abnormality of neuronal migration	Neurodegeneration	Medulloblastoma	Delayed speech and language development	Hyperactivity	Attention deficit hyperactivity disorder	Mental deterioration	Intellectual disability
Disease(s) Associated with NBN
Nijmegen breakage syndrome

Mouse Phenotypes		nervous system phenotype	abnormal neuron differentiation	absent cerebellar foliation	abnormal cerebellum external granule cell layer morphology	decreased brain weight	abnormal cerebellar Purkinje cell layer	abnormal cerebellar granule layer morphology	small cerebellum	abnormal astrocyte morphology
Availability	Mouse Genotype	nervous system phenotype	abnormal neuron differentiation	absent cerebellar foliation	abnormal cerebellum external granule cell layer morphology	decreased brain weight	abnormal cerebellar Purkinje cell layer	abnormal cerebellar granule layer morphology	small cerebellum	abnormal astrocyte morphology
	Nbn^tm1Xu/Nbn^tm1Xu	*
	Nbn^tm2Zqw/Nbn^tm2Zqw Tg(Nes-cre)1Wme/0 (conditional)
	Nbn^tm2Zqw/Nbn^tm2.1Zqw Tg(Nes-cre)1Wme/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23