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Symbol
Name
ID

Akt3
thymoma viral proto-oncogene 3
MGI:1345147

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

increased susceptibility to pharmacologically induced seizures

abnormal seizure response to electrical stimulation

maximal tonic hindlimb extension seizures

tonic-clonic seizures

sporadic seizures

increased susceptibility to neuronal excitotoxicity

decreased brain weight

increased brain weight

decreased brain size

increased brain size

abnormal brain ventricle morphology

decreased corpus callosum size

absent corpus callosum

enlarged hippocampus

ectopic cerebellar granule cells

abnormal neuron morphology

Availability

Mouse Genotype

Akt3^Nmf350/Akt3^Nmf350

Akt3^tm1Hem/Akt3^tm1Hem

Akt3^tm1Mbb/Akt3^tm1Mbb

Akt3^Nmf350/Akt3⁺

Akt3^tm1Mbb/Akt3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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