Symbol
Name
ID

Hivep2
human immunodeficiency virus type I enhancer binding protein 2
MGI:1338076

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Drooling

Frontal cortical atrophy

Thin corpus callosum

Hypoplasia of the corpus callosum

Ataxia

Absent speech

Delayed speech and language development

Anxiety

Autistic behavior

Aggressive behavior

Hyperactivity

Impulsivity

Intellectual disability

Dystonia

Global developmental delay

Delayed ability to crawl

Delayed ability to sit

Delayed ability to walk

Seizure

Disease(s) Associated with HIVEP2

autosomal dominant intellectual developmental disorder 43

Mouse Phenotypes

CNS inflammation

abnormal dentate gyrus morphology

abnormal hippocampus granule cell morphology

abnormal cerebral cortex morphology

abnormal visual cortex morphology

thin cerebral cortex

abnormal cerebellar granule cell morphology

decreased oligodendrocyte number

abnormal dendritic spine morphology

increased dendritic spine length

abnormal dentate gyrus neuron dendrite morphology

decreased neuron number

abnormal astrocyte physiology

abnormal brain wave pattern

abnormal synaptic transmission

decreased prepulse inhibition

Availability

Mouse Genotype

Hivep2^tm1Sis/Hivep2^tm1Sis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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