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Symbol
Name
ID
Pdpk1
3-phosphoinositide dependent protein kinase 1
MGI:1338068
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
nervous system phenotype
increased pituitary gland apoptosis
increased corticotroph apoptosis
increased melanotroph apoptosis
decreased corticotroph cell number
abnormal pituitary intermediate lobe morphology
abnormal melanotroph morphology
abnormal brain development
decreased forebrain size
decreased brain size
abnormal forebrain morphology
absent forebrain
absent dorsal root ganglion
abnormal neuron physiology
Availability Mouse Genotype
Pdpk1tm1.2Mlw/Pdpk1tm1.2Mlw
Pdpk1tm1Dral/Pdpk1tm1Dral
Pdpk1tm1Ejm/Pdpk1tm1Ejm
Pdpk1tm2Ejm/Pdpk1tm2Ejm *
Pdpk1tm1Jcbr/Pdpk1tm1Jcbr
Tg(Pomc1-cre)16Lowl/0  (conditional)
Pdpk1tm1Maka/Pdpk1tm1Maka
Tg(CAG-cat,-lacZ)11Miya/0
Tg(Pomc1-cre)16Lowl/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory