|
Symbol Name ID |
Wfs1
wolframin ER transmembrane glycoprotein MGI:1328355 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Dysphagia |
Spasticity |
Spastic paraplegia |
Basal ganglia calcification |
Atrophy/Degeneration affecting the brainstem |
Cerebral cortical atrophy |
Corpus callosum atrophy |
Abnormal periventricular white matter morphology |
Cerebellar atrophy |
Ataxia |
Hemiparesis |
Dysarthria |
Hallucinations |
Atypical behavior |
Polydipsia |
Cognitive impairment |
Dementia |
Intellectual disability |
Sleep abnormality |
Areflexia |
Gait disturbance |
Migraine |
Developmental regression |
Global developmental delay |
Peripheral neuropathy |
Sensorimotor neuropathy |
Seizure |
Abnormal autonomic nervous system physiology |
| Disease(s) Associated with WFS1 | ||||||||||||||||||||||||||||
| optic atrophy | ||||||||||||||||||||||||||||
| Wolfram syndrome |
| Mouse Phenotypes | nervous system phenotype |
abnormal inner hair cell stereociliary bundle morphology |
fused inner hair cell stereocilia |
absent outer hair cell stereocilia |
cochlear outer hair cell degeneration |
fused vestibular hair cell stereocilia |
vestibular hair cell degeneration |
|
| Availability | Mouse Genotype | |||||||
| Wfs1tm1.1Bedel/Wfs1tm1.1Bedel | * | |||||||
| Wfs1tm1Koks/Wfs1tm1Koks | ||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|
|
||
Analysis Tools