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Symbol
Name
ID
Afdn
afadin, adherens junction formation factor
MGI:1314653
Phenotype annotations related to nervous system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal radial glial cell morphology
increased radial glial cell number
abnormal neural tube morphology
abnormal embryonic neuroepithelium morphology
abnormal neural tube closure
abnormal telencephalon development
thin cortical plate
abnormal cortical ventricular zone morphology
abnormal hindbrain development
increased brain size
abnormal hippocampus morphology
abnormal hippocampus CA1 region morphology
abnormal hippocampus pyramidal cell morphology
ectopic hippocampus pyramidal cells
abnormal cerebral cortex morphology
abnormal neocortex morphology
increased neocortex size
abnormal stratification in cerebral cortex
abnormal nervous system tract morphology
increased neuronal precursor cell number
abnormal synapse morphology
ectopic neuron
abnormal excitatory postsynaptic potential
decreased prepulse inhibition
Availability Mouse Genotype
Afdntm1Mrcr/Afdntm1Mrcr
Afdntm1Ytk/Afdntm1Ytk
Afdnem1(IMPC)Mbp/Afdn+
Afdntm1.1Lfr/Afdntm1.1Lfr
Neurod6tm1(cre)Kan/Neurod6+  (conditional)
Afdntm1c(EUCOMM)Hmgu/Afdntm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+  (conditional)
Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory