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Symbol
Name
ID
Scyl2
SCY1-like 2 (S. cerevisiae)
MGI:1289172
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Spasticity
Frontal cortical atrophy
Parietal cortical atrophy
Agenesis of corpus callosum
Areflexia
Global developmental delay
Seizure
Disease(s) Associated with SCYL2
arthrogryposis multiplex congenita-4

Mouse Phenotypes
increased neuron apoptosis
microgliosis
decreased brain size
decreased dentate gyrus size
decreased hippocampus pyramidal cell number
hippocampal neuron degeneration
small hippocampus
astrocytosis
abnormal excitatory postsynaptic potential
Availability Mouse Genotype
Scyl2tm1.1Spel/Scyl2tm1.1Spel
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory