Symbol
Name
ID

Lrp5
low density lipoprotein receptor-related protein 5
MGI:1278315

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Facial palsy

Dilatation of the cerebral artery

Pituitary growth hormone cell adenoma

Arachnoid cyst

Delayed speech and language development

Intellectual disability, mild

Loss of ambulation

Waddling gait

Headache

Global developmental delay

Delayed gross motor development

Focal impaired awareness seizure

Disease(s) Associated with LRP5

autosomal dominant osteopetrosis 1

autosomal dominant polycystic kidney disease

osteoporosis-pseudoglioma syndrome

polycystic liver disease

Worth syndrome

Mouse Phenotypes		gliosis	retina ganglion cell degeneration	retina photoreceptor degeneration	abnormal blood-retina barrier function
Availability	Mouse Genotype	gliosis	retina ganglion cell degeneration	retina photoreceptor degeneration	abnormal blood-retina barrier function
	Lrp5^tm1Dgen/Lrp5^tm1Dgen
	Lrp5^tvrm111B/Lrp5^tvrm111B

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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