|
Symbol Name ID |
Atg5
autophagy related 5 MGI:1277186 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebellar hypoplasia |
Ataxia |
Dysmetria |
Truncal ataxia |
Babinski sign |
Dysarthria |
Brisk reflexes |
Global developmental delay |
Delayed ability to walk |
| Disease(s) Associated with ATG5 | |||||||||
| autosomal recessive spinocerebellar ataxia 25 |
| Mouse Phenotypes | nervous system phenotype |
abnormal adenohypophysis morphology |
abnormal brain morphology |
abnormal inferior colliculus morphology |
abnormal thalamus morphology |
abnormal hippocampus morphology |
abnormal cerebral cortex morphology |
decreased cerebral cortex pyramidal cell number |
Purkinje cell degeneration |
abnormal cerebellar granule cell morphology |
abnormal axon morphology |
neuron degeneration |
neuronal intranuclear inclusions |
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| Availability | Mouse Genotype | |||||||||||||
| Atg5tm1Nmz/Atg5tm1Nmz | ||||||||||||||
| Atg5tm1Myok/Atg5tm1Myok Tg(Nes-cre)1Kln/? (conditional) |
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| Atg5tm1Myok/Atg5tm1Myok Tg(Pomc1-cre)1Gsb/0 (conditional) |
* | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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