Symbol
Name
ID

Dscam
DS cell adhesion molecule
MGI:1196281

Phenotype annotations related to nervous system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

seizures

abnormal axon fasciculation

abnormal brain morphology

abnormal cerebellar foliation

hydrocephaly

abnormal brain ventricle morphology

enlarged brain ventricles

enlarged lateral ventricles

abnormal lateral ventricle morphology

dilated third ventricle

dilated brain ventricle

enlarged cerebral aqueduct

abnormal brain commissure morphology

abnormal corpus callosum morphology

abnormal brain internal capsule morphology

decreased striatum size

abnormal hippocampus morphology

abnormal cerebral cortex morphology

thin cerebral cortex

small olfactory bulb

abnormal dopaminergic neuron morphology

abnormal neurite morphology

increased neuron number

increased amacrine cell number

increased retina ganglion cell number

abnormal amacrine cell morphology

abnormal retina bipolar cell morphology

abnormal retina cone bipolar cell morphology

abnormal retina ganglion cell morphology

abnormal central pattern generator function

abnormal somatic nervous system physiology

Availability

Mouse Genotype

Dscam^2J/Dscam^2J

Dscam^3J/Dscam^3J

Dscam^del17/Dscam^del17

Dscam^tm1.1Kzy/Dscam^tm1.1Kzy

Dscam^tm1.1Pfu/Dscam^tm1.1Pfu

Dscam^tm1.1Kzy/Dscam⁺

Dscam^tm1Pfu/Dscam^tm1Pfu
Tg(Pax6-cre,GFP)2Pgr/0 (conditional)

Dscam^tm1Pfu/Dscam^tm1Pfu
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Dscam^tm1Pfu/Dscam^tm1Pfu
Tg(Thy1-cre)1Vln/0 (conditional)

Dscam^tm1Pfu/Dscam^tm1Pfu
Opn4^tm1(cre)Sapa/Opn4⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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