Symbol
Name
ID

Nr2e1
nuclear receptor subfamily 2, group E, member 1
MGI:1100526

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal neuron differentiation

abnormal axon fasciculation

decreased radial glial cell number

abnormal neuronal precursor proliferation

abnormal telencephalon development

abnormal cortical intermediate zone morphology

abnormal pallium development

hydrocephaly

forebrain hypoplasia

decreased brain size

enlarged brain ventricles

dilated lateral ventricle

abnormal brain commissure morphology

decreased anterior commissure size

abnormal limbic system morphology

abnormal amygdala morphology

abnormal entorhinal cortex morphology

abnormal dentate gyrus morphology

abnormal hippocampal mossy fiber morphology

small hippocampus

decreased subiculum size

abnormal cerebral hemisphere morphology

small olfactory bulb

abnormal olfactory cortex morphology

abnormal lateral ganglionic eminence morphology

abnormal retina ganglion cell morphology

absent photoreceptor outer segment

abnormal optic nerve morphology

optic nerve degeneration

Availability

Mouse Genotype

Nr2e1^frc/Nr2e1^frc

Nr2e1^tm1Gsc/Nr2e1^tm1Gsc

Nr2e1^tm1Rtyu/Nr2e1^tm1Rtyu

Nr2e1^tm1Rev/Nr2e1^tm1Rtyu

Nr2e1^tm1Rev/Nr2e1^tm1Rev
Tg(CAG-cre/Esr1*)5Amc/? (conditional)

Nr2e1^tm1Rev/Nr2e1^tm1Rev
Tg(Nes-cre)1Kln/0 (conditional)

Nr2e1^tm2Gsc/Nr2e1^tm2Gsc
Tg(Camk2a-cre)2Gsc/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23