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Symbol
Name
ID

Lyst
lysosomal trafficking regulator
MGI:107448

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Photophobia

Spastic paraplegia

Abnormality of the nervous system

Cerebellar atrophy

Brain atrophy

Atrophy of the spinal cord

Neurodegeneration

Ataxia

Parkinsonism

Tremor

Cranial nerve paralysis

Decreased nerve conduction velocity

Cognitive impairment

Dementia

Intellectual disability

Hyporeflexia

Gait disturbance

Inability to walk

Specific learning disability

Peripheral neuropathy

Motor polyneuropathy

Progressive peripheral neuropathy

Sensory neuropathy

Seizure

Somatic sensory dysfunction

Disease(s) Associated with LYST

Chediak-Higashi syndrome

Mouse Phenotypes		abnormal hippocampal mossy fiber morphology	abnormal hippocampus pyramidal cell layer	ectopic hippocampus pyramidal cells	ectopic Bergmann glia cells	decreased Purkinje cell number	ectopic Purkinje cell	ectopic cerebellar granule cells	decreased prepulse inhibition
Availability	Mouse Genotype	abnormal hippocampal mossy fiber morphology	abnormal hippocampus pyramidal cell layer	ectopic hippocampus pyramidal cells	ectopic Bergmann glia cells	decreased Purkinje cell number	ectopic Purkinje cell	ectopic cerebellar granule cells	decreased prepulse inhibition
	Lyst^bg-2J/Lyst^bg-2J
	Lyst^bg-J/Lyst^bg-J
	Lyst^bg/Lyst^bg
	Lyst^{tm1b(EUCOMM)Wtsi}/Lyst^{tm1b(EUCOMM)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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