About Help FAQ

Symbol
Name
ID

Atrx
ATRX, chromatin remodeler
MGI:103067

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Aganglionic megacolon

Infectious encephalitis

Spasticity

Spastic paraplegia

Cerebral cortical atrophy

Agenesis of corpus callosum

Cerebral atrophy

Aphasia

Depression

Atypical behavior

Autism

Motor stereotypy

Self-injurious behavior

Intellectual disability

Abnormality of movement

Global developmental delay

Profound global developmental delay

Seizure

Bilateral tonic-clonic seizure

Disease(s) Associated with ATRX

alpha thalassemia-X-linked intellectual disability syndrome

Mouse Phenotypes		absent dentate gyrus	decreased hippocampus pyramidal cell number	loss of hippocampal neurons	loss of cortex neurons	decreased amacrine cell number	abnormal retina horizontal cell morphology	reduced long-term potentiation
Availability	Mouse Genotype	absent dentate gyrus	decreased hippocampus pyramidal cell number	loss of hippocampal neurons	loss of cortex neurons	decreased amacrine cell number	abnormal retina horizontal cell morphology	reduced long-term potentiation
	Atrx^tm1Enl/Atrx^tm1Enl
	Atrx^tm1Rjg/Y Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)
	Atrx^tm1Rjg/Y Tg(Nes-cre)2472Pick/0 (conditional)
	Atrx^tm1Rjg/Y Tg(Pax6-cre,GFP)2Pgr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23