About Help FAQ

Symbol
Name
ID

Ikzf1
IKAROS family zinc finger 1
MGI:1342540

Phenotype annotations related to neoplasm

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Lymphoma	Hereditary nonpolyposis colorectal carcinoma	Neoplasm of the stomach	Uterine leiomyosarcoma	Renal cell carcinoma	Transitional cell carcinoma of the bladder
Disease(s) Associated with IKZF1	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Lymphoma	Hereditary nonpolyposis colorectal carcinoma	Neoplasm of the stomach	Uterine leiomyosarcoma	Renal cell carcinoma	Transitional cell carcinoma of the bladder
acute lymphoblastic leukemia
colorectal cancer
common variable immunodeficiency 13

Mouse Phenotypes		neoplasm	increased T cell derived lymphoma incidence	increased leukemia incidence	increased lymphoma incidence
Availability	Mouse Genotype	neoplasm	increased T cell derived lymphoma incidence	increased leukemia incidence	increased lymphoma incidence
	Ikzf1^tm1.1Smale/Ikzf1^tm1.1Smale	*
	Ikzf1^tm2.1Smale/Ikzf1^tm2.1Smale
	Ikzf1^plstc/Ikzf1⁺
	Ikzf1^tm1Kge/Ikzf1⁺
	Cd79a^tm1(cre)Reth/Cd79a⁺ Ikzf1^tm3.1Mbu/Ikzf1^tm3.1Mbu (conditional)	*
	Ikzf1^tm3.1Mbu/Ikzf1^tm3.1Mbu Il7r^{tm1.1(icre)Hrr}/Il7r⁺ (conditional)
	Ikzf1^tm3Kge/Ikzf1^tm3Kge Tg(CD2-icre)4Kio/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23