|
Symbol Name ID |
Smo
smoothened, frizzled class receptor MGI:108075 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Breast carcinoma |
Colon cancer |
Neoplasm of the liver |
Hepatocellular carcinoma |
Pancreatic adenocarcinoma |
Ovarian carcinoma |
Melanoma |
| Disease(s) Associated with SMO | |||||||
| hepatocellular carcinoma | |||||||
| pancreatic cancer |
| Mouse Phenotypes | neoplasm |
increased basal cell carcinoma incidence |
increased rhabdomyosarcoma incidence |
increased medulloblastoma incidence |
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| Availability | Mouse Genotype | ||||
| Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols | |||||
| Tg(Neurod2-Smo*A1)199Jols/0 | |||||
| Tg(Neurod2-Smo*A2)#Jols/0 | * | ||||
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/? | * | ||||
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(GFAP-cre)25Mes/0 (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Olig2tm2(TVA,cre)Rth/Olig2+ (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tlx3tm1(cre)Qima/Tlx3+ (conditional) |
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| Gli1tm3(cre/ERT2)Alj/Gli1+ Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Shhtm2(cre/ERT2)Cjt/Shh+ (conditional) |
* | ||||
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(Atoh1-cre/Esr1*)14Fsh/0 (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(Krt1-5-cre/ERT)1Ipc/0 (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/? Tg(CAG-cre/Esr1*)5Amc/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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