|
Symbol Name ID |
Cdkn2a
cyclin dependent kinase inhibitor 2A MGI:104738 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Lymphoma |
Multiple myeloma |
Myelodysplasia |
Breast carcinoma |
Colon cancer |
Neoplasm of the liver |
Neoplasm of the pancreas |
Pancreatic adenocarcinoma |
Prostate cancer |
Ovarian carcinoma |
Renal cell carcinoma |
Bladder neoplasm |
Transitional cell carcinoma of the bladder |
Cutaneous melanoma |
Squamous cell carcinoma |
Astrocytoma |
Neuroblastoma |
Neoplasm of the nervous system |
Melanoma |
| Disease(s) Associated with CDKN2A | ||||||||||||||||||||||
| acute lymphoblastic leukemia | ||||||||||||||||||||||
| acute myeloid leukemia | ||||||||||||||||||||||
| breast cancer | ||||||||||||||||||||||
| head and neck squamous cell carcinoma | ||||||||||||||||||||||
| melanoma and neural system tumor syndrome | ||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||
| myelodysplastic syndrome | ||||||||||||||||||||||
| neuroblastoma | ||||||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||||||
| pancreatic carcinoma | ||||||||||||||||||||||
| prostate cancer | ||||||||||||||||||||||
| renal cell carcinoma | ||||||||||||||||||||||
| urinary bladder cancer |
| Mouse Phenotypes | neoplasm |
increased gastrointestinal stromal tumor incidence |
increased T cell derived lymphoma incidence |
decreased incidence of tumors by chemical induction |
increased incidence of tumors by chemical induction |
increased cutaneous melanoma incidence |
increased fibrohistocytoma incidence |
increased metastatic potential |
increased tumor growth/size |
abnormal tumor incidence |
increased acute lymphoblastic leukemia incidence |
increased lymphoma incidence |
increased B cell derived lymphoma incidence |
increased small lymphocytic lymphoma incidence |
increased histiocytic sarcoma incidence |
increased carcinoma incidence |
increased lung carcinoma incidence |
increased squamous cell carcinoma incidence |
increased melanoma incidence |
increased sarcoma incidence |
increased fibrosarcoma incidence |
increased hemangiosarcoma incidence |
increased osteosarcoma incidence |
increased papilloma incidence |
increased incidence of tumors by ionizing radiation induction |
increased brain tumor incidence |
decreased tumor incidence |
increased tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Cdkn2aem1Cjs/Cdkn2aem1Cjs | |||||||||||||||||||||||||||||
| Cdkn2aem2Cjs/Cdkn2aem2Cjs | * | ||||||||||||||||||||||||||||
| Cdkn2atm1(GFP)Cjs/Cdkn2atm1(GFP)Cjs | |||||||||||||||||||||||||||||
| Cdkn2atm1.1Brn/Cdkn2atm1.1Brn | * | ||||||||||||||||||||||||||||
| Cdkn2atm1Cjs/Cdkn2atm1Cjs | |||||||||||||||||||||||||||||
| Cdkn2atm1Nesh/Cdkn2atm1Nesh | |||||||||||||||||||||||||||||
| Cdkn2atm1Rdp/Cdkn2atm1Rdp | |||||||||||||||||||||||||||||
| Cdkn2atm1Sxs/Cdkn2atm1Sxs | |||||||||||||||||||||||||||||
| Cdkn2atm2.1Brn/Cdkn2atm2.1Brn | |||||||||||||||||||||||||||||
| Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp | |||||||||||||||||||||||||||||
| Cdkn2atm4Cjs/Cdkn2atm4Cjs | * | ||||||||||||||||||||||||||||
| Cdkn2atm1Cjs/Cdkn2a+ | |||||||||||||||||||||||||||||
| Cdkn2atm2.1Rdp/Cdkn2a+ | |||||||||||||||||||||||||||||
| Cdkn2aPctr1-DBA/2N/? | |||||||||||||||||||||||||||||
| Cdkn2atm1.1Gsu/Cdkn2atm1.1Gsu Tg(Pdx1-cre)6Tuv/0 (conditional) |
* | ||||||||||||||||||||||||||||
| Cdkn2atm4Rdp/Cdkn2atm4Rdp Tg(Pdx1-cre)89.1Dam/0 (conditional) |
* | ||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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