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Symbol
Name
ID
Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680
Phenotype annotations related to muscle
Darker colors indicate more annotations
Human Phenotypes
Aplasia/Hypoplasia of the abdominal wall musculature
Flexion contracture
Hypertonia
Hypotonia
Muscle weakness
Generalized muscle weakness
Disease(s) Associated with KRAS
cardiofaciocutaneous syndrome
linear nevus sebaceous syndrome
Lynch syndrome
multiple myeloma
Noonan syndrome
oculoectodermal syndrome

Mouse Phenotypes
increased myocardial fiber number
thin myocardium
increased cardiac muscle contractility
abnormal fetal cardiomyocyte proliferation
Availability Mouse Genotype
Krastm1Mok/Krastm1Mok
Krastm4.1Bbd/Krastm4.1Bbd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory