Symbol
Name
ID

Sgcg
sarcoglycan, gamma (dystrophin-associated glycoprotein)
MGI:1346524

Phenotype annotations related to muscle

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Macroglossia

Achilles tendon contracture

Calf muscle hypertrophy

Calf muscle pseudohypertrophy

Scapular winging

Upper limb muscle weakness

Flexion contracture

EMG: positive sharp waves

EMG: myopathic abnormalities

EMG: myotonic discharges

EMG: myotonic runs

Difficulty climbing stairs

Difficulty running

Frequent falls

Neck flexor weakness

Gowers sign

Type 1 muscle fiber predominance

Increased variability in muscle fiber diameter

Increased endomysial connective tissue

Muscle fiber necrosis

Muscle fiber splitting

Skeletal muscle atrophy

Muscular dystrophy

Disease(s) Associated with SGCG

autosomal recessive limb-girdle muscular dystrophy type 2C

Mouse Phenotypes

muscle phenotype

myocardium necrosis

skeletal muscle necrosis

abnormal tibialis anterior morphology

increased skeletal muscle fiber size

increased variability of skeletal muscle fiber size

centrally nucleated skeletal muscle fibers

abnormal skeletal muscle morphology

abnormal diaphragm morphology

thick diaphragm muscle

skeletal muscle hypertrophy

decreased skeletal muscle mass

increased skeletal muscle mass

skeletal muscle interstitial fibrosis

dystrophic muscle

muscle degeneration

abnormal muscle regeneration

progressive muscle weakness

Availability

Mouse Genotype

Sgcg^tm1Mcn/Sgcg^tm1Mcn

Sgcg^tm1Oza/Sgcg^tm1Oza

Tg(Ckm-Sgcg)4Mcn/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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