|
Symbol Name ID |
Stim1
stromal interaction molecule 1 MGI:107476 |
| Darker colors indicate more annotations |
| Human Phenotypes | Weakness of the intrinsic hand muscles |
Joint contracture |
Flexion contracture |
Abnormality of the musculature |
Hypotonia |
Difficulty running |
Easy fatigability |
Frequent falls |
Increased muscle fatiguability |
Muscle spasm |
Muscle stiffness |
Proximal muscle weakness |
Type 1 muscle fiber predominance |
Increased variability in muscle fiber diameter |
Type 2 muscle fiber atrophy |
Proximal amyotrophy |
Myopathy |
| Disease(s) Associated with STIM1 | |||||||||||||||||
| immunodeficiency 10 | |||||||||||||||||
| Stormorken syndrome | |||||||||||||||||
| tubular aggregate myopathy 1 |
| Mouse Phenotypes | abnormal skeletal muscle fiber mitochondrial morphology |
increased skeletal muscle cell apoptosis |
skeletal muscle necrosis |
myositis |
decreased quadriceps weight |
decreased gastrocnemius weight |
increased soleus weight |
abnormal skeletal muscle fiber morphology |
decreased skeletal muscle fiber diameter |
increased variability of skeletal muscle fiber size |
centrally nucleated skeletal muscle fibers |
abnormal muscle weight |
decreased skeletal muscle weight |
abnormal skeletal muscle morphology |
skeletal muscle fibrosis |
skeletal muscle endomysial fibrosis |
abnormal muscle physiology |
enhanced skeletal muscle regeneration |
impaired muscle relaxation |
decreased muscle fatigability |
muscle weakness |
myopathy |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Stim1tm1.1Pg/Stim1+ | |||||||||||||||||||||||
| Stim1tm3Ics/Stim1+ | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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