Symbol
Name
ID

Otx2
orthodenticle homeobox 2
MGI:97451

Phenotype annotations related to mortality/aging

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

mortality/aging

premature death

neonatal lethality, complete penetrance

neonatal lethality, incomplete penetrance

perinatal lethality, incomplete penetrance

postnatal lethality

postnatal lethality, complete penetrance

postnatal lethality, incomplete penetrance

embryonic lethality during organogenesis, complete penetrance

prenatal lethality, complete penetrance

preweaning lethality, incomplete penetrance

Availability

Mouse Genotype

Otx2^tm1Pas/Otx2^tm1Pas

Otx2^tm1Sia/Otx2^tm1Sia

Otx2^tm1Sla/Otx2^tm1Sla

Otx2^tm3Tlam/Otx2^tm3Tlam

Otx2^tm4Sia/Otx2^tm4Sia

Otx2^tm11Asim/Otx2^tm11Asim

Otx2^tm12.1Asim/Otx2^tm12.1Asim

Otx2^tm1Pas/Otx2⁺

Otx2^tm1Sia/Otx2⁺

Otx2^tm1Sla/Otx2⁺

Otx2^tm12.1Asim/Otx2^tm11Asim

H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Tg(CAG-Otx2,-EGFP)1Eno/? (conditional)

Otx1^tm4(cre)Asim/Otx1⁺
Otx2^tm6Asim/Otx2^tm6.1Asim (conditional)

Otx2^tm1.1Tlam/Otx2^{tm2(cre/ERT2)Tlam} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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