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Symbol
Name
ID

Tfam
transcription factor A, mitochondrial
MGI:107810

Phenotype annotations related to mortality/aging

Darker colors indicate more annotations

Human Phenotypes	Death in infancy
Disease(s) Associated with TFAM	Death in infancy
mitochondrial DNA depletion syndrome 15

Mouse Phenotypes		premature death	neonatal lethality, incomplete penetrance	postnatal lethality, complete penetrance	embryonic lethality during organogenesis, complete penetrance
Availability	Mouse Genotype	premature death	neonatal lethality, incomplete penetrance	postnatal lethality, complete penetrance
	Tfam^tm1.1Lrsn/Tfam^tm1.1Lrsn
	Tfam^tm1.1Ncdl/Tfam^tm1.1Ncdl Tg(KRT14-cre)1Amc/0 (conditional)
	Tfam^tm1Lrsn/Tfam^tm1Lrsn Tg(Ckmm-cre)1Lrsn/0 (conditional)
	Tfam^tm1Lrsn/Tfam^tm1Lrsn Tg(Myhca-cre)1Lrsn/0 (conditional)
	Tfam^tm1Lrsn/Tfam^tm1Lrsn Tg(Camk2a-cre)1Lfr/0 (conditional)
	Myl1^tm1(cre)Sjb/Myl1⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn (conditional)
	Slc6a3^tm1(cre)Lrsn/Slc6a3⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn (conditional)
	Cnp^tm1(cre)Kan/Cnp⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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