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Symbol
Name
ID

Trp53
transformation related protein 53
MGI:98834

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatocellular carcinoma
Disease(s) Associated with TP53	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatocellular carcinoma
hepatocellular carcinoma
pancreatic cancer

Mouse Phenotypes		enlarged liver	hepatosplenomegaly	liver hyperplasia	liver inflammation	decreased liver weight	liver hypoplasia	hepatic steatosis	liver cirrhosis	increased liver tumor incidence	increased hepatocellular carcinoma incidence
Availability	Mouse Genotype	enlarged liver	hepatosplenomegaly	liver hyperplasia	liver inflammation	decreased liver weight	liver hypoplasia	hepatic steatosis	liver cirrhosis	increased liver tumor incidence	increased hepatocellular carcinoma incidence
	Trp53^tm1.1Xlu/Trp53^tm1.1Xlu
	Trp53^tm1.2Awbr/Trp53^tm1.2Awbr
	Trp53^tm1Yjc/Trp53^tm1Yjc
	Trp53^tm1.2Awbr/Trp53⁺
	Trp53^tm1Ldo/Trp53⁺
	Trp53^tm3.1Glo/Trp53⁺
	Trp53^tm3.1Tyj/Trp53⁺
	Tg(Trp53A135V)L3Ber/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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