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Symbol
Name
ID
Fas
Fas cell surface death receptor
MGI:95484
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the hepatic vasculature
Hepatosplenomegaly
Hepatomegaly
Abnormality of the liver
Cirrhosis
Hepatitis
Biliary cirrhosis
Hepatocellular carcinoma
Disease(s) Associated with FAS
autoimmune lymphoproliferative syndrome
cystic fibrosis
pre-eclampsia

Mouse Phenotypes
decreased hepatocyte apoptosis
focal hepatic necrosis
liver hyperplasia
liver inflammation
abnormal liver morphology
abnormal hepatocyte morphology
abnormal liver physiology
Availability Mouse Genotype
Faslpr/Faslpr
Fastm1Osa/Fastm1Osa
Fastm1Ach/Fastm1Ach
Tg(Itgax-cre,-EGFP)4097Ach/?  (conditional)
Fastm1Cgn/Fastm1Cgn
Tg(Cd4-cre)1Cwi/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory