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Symbol
Name
ID

Gclc
glutamate-cysteine ligase, catalytic subunit
MGI:104990

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Hepatomegaly	Abnormality of the liver	Cirrhosis	Biliary cirrhosis	Jaundice
Disease(s) Associated with GCLC	Hepatosplenomegaly	Hepatomegaly	Abnormality of the liver	Cirrhosis	Biliary cirrhosis	Jaundice
cystic fibrosis
glutamate-cysteine ligase deficiency

Mouse Phenotypes		abnormal liver morphology	hepatic steatosis	abnormal liver physiology
Availability	Mouse Genotype	abnormal liver morphology	hepatic steatosis	abnormal liver physiology
	Gclc^tm1Dwn/Gclc⁺
	Gclc^tm1Tdal/Gclc^tm1Tdal Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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