Symbol
Name
ID

Bmp4
bone morphogenetic protein 4
MGI:88180

Phenotype annotations related to limbs/digits/tail

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Clinodactyly of the 5th finger

Short middle phalanx of finger

Proximal placement of thumb

Thumb contracture

Postaxial foot polydactyly

Toe syndactyly

Polydactyly

Brachydactyly

Finger syndactyly

Palmoplantar hyperhidrosis

Abnormality of the hand

Single transverse palmar crease

Palmar hyperkeratosis

Disease(s) Associated with BMP4

syndromic microphthalmia 6

tooth agenesis

Mouse Phenotypes		limbs/digits/tail phenotype	sirenomelia	abnormal hindlimb bud morphology	polydactyly	preaxial polydactyly	abnormal forelimb morphology	abnormal fibula morphology	abnormal limb development
Availability	Mouse Genotype	limbs/digits/tail phenotype	sirenomelia	abnormal hindlimb bud morphology	polydactyly	preaxial polydactyly	abnormal forelimb morphology	abnormal fibula morphology	abnormal limb development
	Bmp4^tm1.1Jlch/Bmp4^tm1.1Jlch
	Bmp4^tm1.1Jlch/Bmp4^tm2Blh
	Bmp4^tm1Blh/Bmp4⁺
	Tg(Krt14-Bmp4)#Jake/0	*
	Bmp4^tm1Jfm/Bmp4^tm1Jfm Tg(Prrx1-cre)1Cjt/0 (conditional)
	Bmp4^tm4Blh/Bmp4^tm4Blh Isl1^tm1(cre)Sev/Isl1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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