|
Symbol Name ID |
Shh
sonic hedgehog MGI:98297 |
| Darker colors indicate more annotations |
| Human Phenotypes | Highly arched eyebrow |
Synophrys |
Thick eyebrow |
Nail dysplasia |
| Disease(s) Associated with SHH | ||||
| holoprosencephaly | ||||
| polydactyly |
| Mouse Phenotypes | decreased keratinocyte proliferation |
alopecia |
abnormal hair shaft morphology |
abnormal hair follicle morphology |
abnormal hair follicle development |
absent hair follicle inner root sheath |
abnormal hair follicle orientation |
absent hair follicles |
absent vibrissae |
abnormal dermal layer morphology |
abnormal dermis papillary layer morphology |
abnormal epidermal layer morphology |
epidermal hyperplasia |
thick epidermis |
shiny skin |
tight skin |
translucent skin |
increased basal cell carcinoma incidence |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Shhtm1Amc/Shhtm1Amc | |||||||||||||||||||
| Tg(KRT14-Shh)#Cobm/0 | |||||||||||||||||||
| Shhtm1Amc/Shhtm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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