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Symbol
Name
ID
Rac1
Rac family small GTPase 1
MGI:97845
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Highly arched eyebrow
Synophrys
Eczematoid dermatitis
Disease(s) Associated with RAC1
autosomal dominant intellectual developmental disorder 48

Mouse Phenotypes
abnormal sebocyte number
enlarged sebaceous gland
abnormal coat/ hair morphology
alopecia
abnormal hair shaft morphology
abnormal hair follicle morphology
absent hair follicle bulb
abnormal hair follicle infundibulum morphology
abnormal hair follicle bulge morphology
abnormal hair cycle
abnormal epidermal layer morphology
abnormal epidermis stratum basale morphology
abnormal skin cell number
abnormal skin pigmentation
abnormal skin condition
abnormal skin physiology
abnormal keratinocyte physiology
Availability Mouse Genotype
Rac1tm1Brak/Rac1tm1Brak
Tg(KRT5-cre)5132Jlj/0  (conditional)
Rac1tm1Djk/Rac1tm1Djk
Tg(KRT14-cre/ERT)20Efu/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory