Symbol Name ID |
Notch1
notch 1 MGI:97363 |
Darker colors indicate more annotations |
Human Phenotypes | Low anterior hairline |
Single transverse palmar crease |
Supernumerary nipple |
Cutis marmorata |
Alopecia |
Sparse hair |
Hypoplastic fingernail |
Hypoplastic fifth fingernail |
Aplastic/hypoplastic toenail |
Absent toenail |
Hypoplastic toenails |
Dystrophic toenail |
Toenail dysplasia |
Absent fingernail |
Small nail |
Aplasia/Hypoplasia of the skin |
Aplasia cutis congenita |
Aplasia cutis congenita over posterior parietal area |
Aplasia cutis congenita on trunk or limbs |
Cutis marmorata telangiectatica congenita |
Disease(s) Associated with NOTCH1 | ||||||||||||||||||||
Adams-Oliver syndrome |
Mouse Phenotypes | Meibomian gland degeneration |
small sebaceous gland |
diluted coat color |
abnormal hair growth |
alopecia |
focal hair loss |
short hair |
waved hair |
abnormal hair shaft morphology |
decreased curvature of zigzag hairs |
deformed nails |
abnormal hair follicle morphology |
disorganized inner root sheath cells |
curly vibrissae |
short vibrissae |
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Availability | Mouse Genotype | |||||||||||||||
Tg(Notch1)1Anc/0 | ||||||||||||||||
Tg(Notch1)A5Rko/0 | ||||||||||||||||
Tg(Notch1)A7Rko/0 | ||||||||||||||||
Notch1tm1Agt/Notch1tm1Agt Tg(Tyr-cre)2Lru/0 (conditional) |
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Notch1tm2Rko/Notch1tm2Rko Tg(Msx2-cre)5Rem/0 (conditional) |
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Notch1tm2Rko/Notch1tm2Rko Tg(KRT14-rtTA)F42Efu/0 Tg(tetO-cre)1Jaw/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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