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Symbol
Name
ID
Krt2
keratin 2
MGI:96699
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Palmoplantar keratoderma
Erythema
Abnormal blistering of the skin
Acantholysis
Thin skin
Ichthyosis
Congenital bullous ichthyosiform erythroderma
Disease(s) Associated with KRT2
bullous congenital ichthyosiform erythroderma

Mouse Phenotypes
abnormal keratinocyte differentiation
increased keratinocyte proliferation
increased ear pigmentation
impaired skin barrier function
skin inflammation
abnormal corneocyte morphology
hyperkeratosis
orthokeratosis
thick epidermis stratum granulosum
hypergranulosis
acanthosis
abnormal epidermis suprabasal layer morphology
epidermal hyperplasia
thick epidermis
scaly skin
abnormal skin pigmentation
increased foot pad pigmentation
increased tail pigmentation
Availability Mouse Genotype
Krt2Mhdadsk2/Krt2Mhdadsk2
Krt2tm1a(KOMP)Wtsi/Krt2tm1a(KOMP)Wtsi
Krt2Mhdadsk2/Krt2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory