|
Symbol Name ID |
Irf6
interferon regulatory factor 6 MGI:1859211 |
| Darker colors indicate more annotations |
| Human Phenotypes | Sparse scalp hair |
Lower lip pit |
Lip pit |
Absent eyebrow |
Absent eyelashes |
Absent palmar crease |
Wide intermamillary distance |
Alopecia |
Alopecia totalis |
Generalized hirsutism |
Abnormality of the nail |
Anonychia |
Small nail |
Pyramidal skinfold extending from the base to the top of the nails |
Dry skin |
Skin tags |
Pterygium |
Axillary pterygium |
Intercrural pterygium |
Popliteal pterygium |
| Disease(s) Associated with IRF6 | ||||||||||||||||||||
| popliteal pterygium syndrome | ||||||||||||||||||||
| Van der Woude syndrome |
| Mouse Phenotypes | abnormal keratinocyte differentiation |
increased keratinocyte proliferation |
decreased hair follicle number |
absent vibrissae |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
absent epidermis stratum corneum |
absent epidermis stratum granulosum |
abnormal epidermis stratum spinosum morphology |
abnormal epidermis suprabasal layer morphology |
abnormal keratinocyte morphology |
thick epidermis |
shiny skin |
tight skin |
abnormal skin development |
delayed skin barrier formation |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Irf6clft1/Irf6clft1 | |||||||||||||||||
| Irf6Gt(OST398253)Lex/Irf6Gt(OST398253)Lex | |||||||||||||||||
| Irf6tm1.1Bcsl/Irf6tm1.1Bcsl | |||||||||||||||||
| Irf6tm1Mjd/Irf6tm1Mjd | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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