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Symbol
Name
ID

Lyst
lysosomal trafficking regulator
MGI:107448

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Bruising susceptibility	Jaundice	Recurrent bacterial skin infections	Skin rash	Hypopigmentation of hair	Silver-gray hair	Large clumps of pigment irregularly distributed along hair shaft	Giant melanosomes in melanocytes	Spotty hyperpigmentation	Hypopigmentation of the skin	Cutaneous photosensitivity
Disease(s) Associated with LYST
Chediak-Higashi syndrome

Mouse Phenotypes

decreased ear pigmentation

abnormal dermal mast cell morphology

abnormal coat/hair pigmentation

abnormal hair follicle melanocyte morphology

absent hair follicle melanin granules

enlarged hair follicle melanin granules

abnormal hair shaft melanin granule shape

diluted coat color

premature hair loss

delayed hair regrowth

abnormal skin morphology

abnormal dermal layer morphology

abnormal skin pigmentation

abnormal foot pigmentation

decreased tail pigmentation

Availability

Mouse Genotype

Lyst^bg-2Btlr/Lyst^bg-2Btlr

Lyst^bg-2J/Lyst^bg-2J

Lyst^bg-3Btlr/Lyst^bg-3Btlr

Lyst^bg-4Btlr/Lyst^bg-4Btlr

Lyst^bg-7Btlr/Lyst^bg-7Btlr

Lyst^bg-8Btlr/Lyst^bg-8Btlr

Lyst^bg-8J/Lyst^bg-8J

Lyst^bg-9Btlr/Lyst^bg-9Btlr

Lyst^bg-10Btlr/Lyst^bg-10Btlr

Lyst^bg-10J/Lyst^bg-10J

Lyst^bg-11Btlr/Lyst^bg-11Btlr

Lyst^bg-11J/Lyst^bg-11J

Lyst^bg-14J/Lyst^bg-14J

Lyst^bg-16J/Lyst^bg-16J

Lyst^bg-18J/Lyst^bg-18J

Lyst^bg-Btlr/Lyst^bg-Btlr

Lyst^bg-grey/Lyst^bg-grey

Lyst^bg-Lac/Lyst^bg-Lac

Lyst^bg-slt/Lyst^bg-slt

Lyst^bg/Lyst^bg

Lyst^{tm1b(EUCOMM)Wtsi}/Lyst^{tm1b(EUCOMM)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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