|
Symbol Name ID |
Stat3
signal transducer and activator of transcription 3 MGI:103038 |
| Darker colors indicate more annotations |
| Human Phenotypes | Breast carcinoma |
Erythema |
Cutaneous abscess |
Recurrent cutaneous abscess formation |
Eczematoid dermatitis |
Erythema nodosum |
Chronic mucocutaneous candidiasis |
Chronic oral candidiasis |
Skin rash |
Abnormal hair morphology |
Patchy alopecia |
Dystrophic fingernails |
Paronychia |
Generalized abnormality of skin |
Papule |
Skin ulcer |
Skin vesicle |
Pruritus |
Squamous cell carcinoma |
| Disease(s) Associated with STAT3 | |||||||||||||||||||
| Behcet's disease | |||||||||||||||||||
| breast cancer | |||||||||||||||||||
| head and neck squamous cell carcinoma | |||||||||||||||||||
| hyper IgE recurrent infection syndrome 1 | |||||||||||||||||||
| ovarian cancer |
| Mouse Phenotypes | decreased keratinocyte migration |
increased keratinocyte proliferation |
dermatitis |
abnormal hair follicle morphology |
decreased hair follicle number |
abnormal hair cycle anagen phase |
abnormal skin morphology |
mixed cellular infiltration to dermis |
abnormal epidermal layer morphology |
hyperkeratosis |
parakeratosis |
absent epidermis stratum granulosum |
acanthosis |
reddish skin |
scaly skin |
spontaneous skin ulceration |
psoriasis |
thick skin |
skin fibrosis |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 | ||||||||||||||||||||
| Stat3tm2Aki/Stat3tm2Aki Tg(KRT5-cre/ERT2)AJdg/0 (conditional) |
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| Stat3tm2Aki/Stat3tm2Aki Tg(KRT5-cre)1Tak/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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