Symbol Name ID |
Cbfb
core binding factor beta MGI:99851 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal thymus morphology |
abnormal thymus cell ratio |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
enlarged spleen |
abnormal T cell differentiation |
abnormal CD4-positive T cell differentiation |
abnormal T-helper 1 cell differentiation |
abnormal CD8-positive, alpha-beta T cell differentiation |
abnormal double-positive T cell morphology |
decreased double-positive T cell number |
increased double-positive T cell number |
abnormal myelopoiesis |
increased CD4-positive, alpha-beta T cell number |
abnormal CD8-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
absent T cells |
decreased lymphocyte cell number |
increased leukocyte cell number |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal spleen morphology |
small spleen |
spleen hypoplasia |
abnormal splenic cell ratio |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased immunoglobulin level |
abnormal lymph organ development |
decreased Peyer's patch number |
absent Peyer's patches |
abnormal peripheral lymph node morphology |
lung inflammation |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm1Spe Tg(Tek-GFP/Cbfb)1Spe/0 |
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Cbfbtm1Spe/Cbfbtm1Spe Tg(Tek-GFP/Cbfb)2Spe/0 |
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Cbfbtm1Tok/Cbfbtm1Tok Tg(Gata1-Cbfb)1Tok/0 |
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Cbfbtm2.1Spe/Cbfbtm2.1Spe | |||||||||||||||||||||||||||||||||||
Cbfbtm2Itan/Cbfbtm2Itan | |||||||||||||||||||||||||||||||||||
Cbfbtm1Spe/Cbfbtm2.1Spe | |||||||||||||||||||||||||||||||||||
Cbfbtm1Itan/Cbfbtm1Itan Tg(Lck-cre)1Cwi/0 (conditional) |
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Cbfbtm1Itan/Cbfbtm1Itan Tg(Cd4-cre)1Cwi/0 (conditional) |
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Cbfbtm1Lhc/Cbfbtm1Lhc Tg(Mx1-cre)1Cgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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