About   Help   FAQ
Symbol
Name
ID 		Cbfb
core binding factor beta
MGI:99851
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal thymus morphology
abnormal thymus cell ratio
small thymus
thymus hypoplasia
decreased thymocyte number
enlarged spleen
abnormal T cell differentiation
abnormal CD4-positive T cell differentiation
abnormal T-helper 1 cell differentiation
abnormal CD8-positive, alpha-beta T cell differentiation
abnormal double-positive T cell morphology
decreased double-positive T cell number
increased double-positive T cell number
abnormal myelopoiesis
increased CD4-positive, alpha-beta T cell number
abnormal CD8-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
absent T cells
decreased lymphocyte cell number
increased leukocyte cell number
abnormal CD8-positive, alpha beta T cell morphology
abnormal spleen morphology
small spleen
spleen hypoplasia
abnormal splenic cell ratio
increased IgA level
increased IgE level
increased IgG1 level
increased immunoglobulin level
abnormal lymph organ development
decreased Peyer's patch number
absent Peyer's patches
abnormal peripheral lymph node morphology
lung inflammation
Availability Mouse Genotype
Cbfbtm1Spe/Cbfbtm1Spe
Tg(Tek-GFP/Cbfb)1Spe/0
Cbfbtm1Spe/Cbfbtm1Spe
Tg(Tek-GFP/Cbfb)2Spe/0
Cbfbtm1Tok/Cbfbtm1Tok
Tg(Gata1-Cbfb)1Tok/0
Cbfbtm2.1Spe/Cbfbtm2.1Spe
Cbfbtm2Itan/Cbfbtm2Itan
Cbfbtm1Spe/Cbfbtm2.1Spe
Cbfbtm1Itan/Cbfbtm1Itan
Tg(Lck-cre)1Cwi/0  (conditional)
Cbfbtm1Itan/Cbfbtm1Itan
Tg(Cd4-cre)1Cwi/0  (conditional)
Cbfbtm1Lhc/Cbfbtm1Lhc
Tg(Mx1-cre)1Cgn/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory