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Symbol
Name
ID

Runx2
runt related transcription factor 2
MGI:99829

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Sinusitis	Chronic otitis media	Recurrent respiratory infections
Disease(s) Associated with RUNX2
cleidocranial dysplasia

Mouse Phenotypes		abnormal osteoclast differentiation	enlarged thymus	decreased thymocyte number	enlarged spleen	increased granulocyte number	decreased B cell number	increased osteoclast cell number	abnormal splenic cell ratio
Availability	Mouse Genotype	abnormal osteoclast differentiation	enlarged thymus	decreased thymocyte number	enlarged spleen	increased granulocyte number	decreased B cell number	increased osteoclast cell number	abnormal splenic cell ratio
	Runx2^tm1Kish/Runx2^tm1Kish
	Runx2^tm1Kish/Runx2⁺
	Tg(Col1a1-Runx2)#Pmt/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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