|
Symbol Name ID |
Ccl7
C-C motif chemokine ligand 7 MGI:99512 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA concentration |
Increased circulating IgE concentration |
Decreased total leukocyte count |
Increased total leukocyte count |
Recurrent pharyngitis |
Pericarditis |
Lymphadenopathy |
Mediastinal lymphadenopathy |
Splenomegaly |
Subacute progressive viral hepatitis |
Pancreatitis |
Episcleritis |
Iridocyclitis |
Epididymitis |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Increased circulating interleukin 6 concentration |
Eczematoid dermatitis |
Erythema nodosum |
Pustule |
Skin rash |
Discoid lupus rash |
Malar rash |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Anti-complement component C1q antibody positivity |
Anti-phosphatidic acid antibody positivity |
Anti-ribosome Po antibody positivity |
Anti-Ro52/TRIM21 antibody positivity |
Anti-titin antibody positivity |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-nucleoporin 62 antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Systemic lupus erythematosus |
Asthma |
Infectious encephalitis |
Meningitis |
| Disease(s) Associated with CCL2 | |||||||||||||||||||||||||||||||||||||||||||||
| asthma | |||||||||||||||||||||||||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||||||||||||||||||||||||
| hepatocellular carcinoma | |||||||||||||||||||||||||||||||||||||||||||||
| IgA vasculitis | |||||||||||||||||||||||||||||||||||||||||||||
| pancreatitis | |||||||||||||||||||||||||||||||||||||||||||||
| systemic lupus erythematosus | |||||||||||||||||||||||||||||||||||||||||||||
| temporal arteritis | |||||||||||||||||||||||||||||||||||||||||||||
| thrombocytopenia | |||||||||||||||||||||||||||||||||||||||||||||
| Disease(s) Associated with CCL11 | |||||||||||||||||||||||||||||||||||||||||||||
| asthma | |||||||||||||||||||||||||||||||||||||||||||||
| Mouse Phenotypes | immune system phenotype |
abnormal dendritic cell chemotaxis |
abnormal macrophage chemotaxis |
impaired macrophage chemotaxis |
abnormal leukocyte migration |
abnormal microglial cell physiology |
decreased susceptibility to induced colitis |
decreased eosinophil cell number |
increased neutrophil cell number |
decreased dendritic cell number |
increased CD4-positive, alpha-beta T cell number |
decreased lymphocyte cell number |
decreased macrophage cell number |
increased osteoclast cell number |
decreased leukocyte cell number |
abnormal monocyte morphology |
impaired eosinophil recruitment |
abnormal neutrophil physiology |
increased IgG1 level |
increased IgG level |
abnormal T cell physiology |
abnormal macrophage physiology |
increased circulating interferon-gamma level |
increased circulating interleukin-10 level |
increased circulating tumor necrosis factor level |
abnormal chemokine level |
abnormal dendritic cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal cytokine secretion |
abnormal chemokine secretion |
decreased interferon-gamma secretion |
decreased interleukin-1 beta secretion |
increased interleukin-10 secretion |
decreased interleukin-12b secretion |
decreased interleukin-4 secretion |
decreased interleukin-5 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
decreased inflammatory response |
increased susceptibility to bacterial infection |
increased susceptibility to infection induced morbidity/mortality |
increased susceptibility to parasitic infection |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Tyos/Ccl2tm1.1Tyos | ||||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Lex/Ccl2tm1Lex | * | |||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Rol/Ccl2tm1Rol | ||||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Rol/Ccl2tm1Rol Tg(Ccr2-EGFP)8Pame/0 |
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| Ccl2tm1Tyos/Ccl2tm1Tyos | ||||||||||||||||||||||||||||||||||||||||||
| Ccl7tm1Ifc/Ccl7tm1Ifc | ||||||||||||||||||||||||||||||||||||||||||
| Ccl11tm1Mer/Ccl11tm1Mer | ||||||||||||||||||||||||||||||||||||||||||
| Ccl12tm1.1Ifc/Ccl12tm1.1Ifc | * | |||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Tg(Nes-cre)1Kln/0 (conditional) |
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| Ccl2tm1.1Pame/Ccl2tm1.1Pame Tg(Tek-cre)12Flv/0 (conditional) |
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| Ccl2tm1.1Pame/Ccl2tm1.1Pame Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/24/2026 MGI 6.24 |
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