Symbol Name ID |
Spta1
spectrin alpha, erythrocytic 1 MGI:98385 |
Darker colors indicate more annotations |
Human Phenotypes | Splenomegaly |
Maculopapular exanthema |
Disease(s) Associated with SPTA1 | ||
hereditary spherocytosis |
Mouse Phenotypes | increased B cell proliferation |
increased T cell proliferation |
enlarged spleen |
increased spleen weight |
increased neutrophil cell number |
increased B cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
increased T cell number |
increased lymphocyte cell number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
decreased spleen iron level |
abnormal splenic cell ratio |
increased IgA level |
increased IgG level |
abnormal lymph node cell ratio |
lymph node hyperplasia |
glomerulonephritis |
tubular nephritis |
alveolitis |
interstitial pneumonia |
increased susceptibility to bacterial infection |
decreased susceptibility to parasitic infection |
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Availability | Mouse Genotype | |||||||||||||||||||||||||
Spta1ihj/Spta1ihj | ||||||||||||||||||||||||||
Spta1sph-2Bc/Spta1sph-2Bc | ||||||||||||||||||||||||||
Spta1sph-3J/Spta1sph-3J | ||||||||||||||||||||||||||
Spta1sph-4J/Spta1sph-4J | ||||||||||||||||||||||||||
Spta1sph-Dem/Spta1sph-Dem | ||||||||||||||||||||||||||
Spta1sph-ha/Spta1sph-ha | ||||||||||||||||||||||||||
Spta1sph/Spta1sph |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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