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Symbol Name ID |
Rel
reticuloendotheliosis oncogene MGI:97897 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
impaired macrophage chemotaxis |
decreased B cell proliferation |
decreased T cell proliferation |
enlarged spleen |
abnormal T cell differentiation |
abnormal CD4-positive T cell differentiation |
abnormal T-helper 1 cell differentiation |
increased eosinophil cell number |
decreased B-1 B cell number |
abnormal memory B cell number |
decreased central memory CD4-positive, alpha-beta T cell number |
decreased effector memory CD4-positive, alpha-beta T cell number |
increased effector memory CD4-positive, alpha-beta T cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased alpha-beta T cell number |
increased T cell number |
decreased monocyte cell number |
abnormal macrophage morphology |
abnormal spleen morphology |
increased spleen B cell follicle size |
decreased spleen germinal center number |
abnormal splenic cell ratio |
abnormal leukocyte physiology |
increased IgA level |
decreased IgE level |
decreased IgG1 level |
decreased IgG2a level |
increased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgG level |
decreased IgM level |
increased IgM level |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal macrophage physiology |
enlarged lymph nodes |
abnormal professional antigen presenting cell physiology |
abnormal dendritic cell physiology |
abnormal humoral immune response |
impaired humoral immune response |
abnormal cytokine secretion |
decreased susceptibility to autoimmune diabetes |
decreased susceptibility to experimental autoimmune encephalomyelitis |
dermatitis |
increased susceptibility to bacterial infection |
decreased susceptibility to parasitic infection |
decreased response to antigen |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| RelM1Btlr/RelM1Btlr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RelM2Btlr/RelM2Btlr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Relm3Btlr/Relm3Btlr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1b(EUCOMM)Wtsi/Reltm1b(EUCOMM)Wtsi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1Brv/Reltm1Brv | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1Grd/Reltm1Grd | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1Hcl/Reltm1Hcl | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| RelM1Btlr/Rel+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1Grd/Rel+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reltm1Hcl/Rel+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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