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Symbol
Name
ID

Pomc
pro-opiomelanocortin-alpha
MGI:97742

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Neutrophilia	Leukocytosis	Pericarditis	Lymphadenopathy	Splenomegaly	Crohn's disease	Peritonitis	Pancreatitis	Erysipelas	Skin rash	Meningitis
Disease(s) Associated with POMC
familial Mediterranean fever

Mouse Phenotypes		increased splenocyte proliferation	enlarged spleen	abnormal spleen morphology	increased circulating interleukin-6 level	increased interleukin-6 secretion	increased tumor necrosis factor secretion
Availability	Mouse Genotype	increased splenocyte proliferation	enlarged spleen	abnormal spleen morphology	increased circulating interleukin-6 level	increased interleukin-6 secretion	increased tumor necrosis factor secretion
	Pomc^tm1Low/Pomc^tm1Low
	Pomc^{em1(IMPC)Rbrc}/Pomc⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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