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Symbol Name ID |
Pcsk1
proprotein convertase subtilisin/kexin type 1 MGI:97511 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | enlarged spleen |
abnormal T-helper 1 cell differentiation |
decreased NK T cell number |
decreased T cell number |
increased lymphocyte cell number |
abnormal peritoneal macrophage morphology |
intermingled spleen red and white pulp |
abnormal spleen white pulp morphology |
abnormal spleen marginal zone morphology |
increased circulating interferon-gamma level |
increased circulating interleukin-1 beta level |
increased circulating interleukin-10 level |
increased circulating interleukin-12 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased follicular dendritic cell number |
increased interleukin-1 beta secretion |
increased susceptibility to endotoxin shock |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Pcsk1tm1Dfs/Pcsk1tm1Dfs | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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